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Anesthesia May Affect Child Development
Early research suggests a possible link between exposure to general anesthesia in infancy and early...
2008-10-27 07:54:20
How scent brings back memories of emotional events
Washington, Oct 17 ANI: A new study in mice, conducted by researchers at the Duke University Medical Center, has shown that the part of the brain that processes scents is indeed a key part of forming long-term memories, especially involving other individuals.During the study, the researchers examined how strong memories are formed by creating new memories in the minds of mice while under sedation and monitoring their response to a memory-inducing stimulus afterwards, when they were awake."Our work is unique because it allows us to examine the cellular make-up of a memory, evaluate how the neurons change when a memory is formed and learn how that memory affects behaviour," said Stephen Shea, Ph.D., the lead author of the study. The researchers created memories by stimulating the release of noradrenaline - a chemical present in the body during strong emotional events ranging from excitement to fear.Previous studies have established a link between noradrenaline and the formation of enduring memories, especially during intense social events such as mating and childbirth. In mice and humans, the presence of noradrenaline also creates changes in the odour-processing center of the brain, called the olfactory bulb. "When an animal forms a strong memory about another, it is reliant on odour cues and noradrenaline. Both need to be present at the same time in order for the memory to be formed. Long-term memories created under these conditions often result in a permanent change in behaviour," Shea said.The researchers administered anesthesia to a mouse and stimulated the release of noradrenaline with an electrode while wafting the scent of either food or the urine of another mouse under the nose."We wanted to see if these two elements - noradrenaline and odour - present at the same time were the key ingredients needed in the recipe for creation of memory - this is a concept that had not been directly tested before this study. In essence, we recreated the chemical reaction that would occur when the mouse experiences a social event, such as giving birth," Shea said.Researchers knew they could observe brain activity in more detail when the mouse was under anesthesia. If awake, the mouse would be forming memories from the surrounding environment. "When the animal is asleep, you can watch neurons in the brain rewire to store a memory and once awake see what the mouse learned even though it was asleep when the memory was created," Shea said.Researchers saw an approximate 40 percent reduction in neuron activation after triggering the noradrenaline release - suggesting that a memory of the odour had been formed. A day later, after the mouse was awake, the researchers observed changes in behaviour in response to the scents, showing that they remembered the smells from when they were asleep. "This work may have implications for furthering our understanding of how long-lasting memories are formed that are important to social bonding," said Richard Mooney, Ph.D., co-author and associate professor of neurobiology.The study is published in the Journal of Neuroscience. ANI
2008-10-17 05:00:00
Acupuncture anesthesia gives child new chance
A 10-YEAR-OLD boy from a poor family in Sichuan Province finally received an operation to treat his congenital heart disease, thanks to a Shanghai hospital that used acupuncture anesthesia to reduce side effects and...
2008-08-00 00:00:00
New Jersey Court Upholds Tightened Anesthesia Rules
The New Jersey Appellate Division has upheld tighter state regulations governing the use of anesthesia during procedures performed in a doctor's office.
2008-08-08 16:49:52
FDA Puts Schering-Plough Under
Newly cautious agency unexpectedly keeps post-anesthesia drug off market.
2008-08-02 22:19:43
FDA rejects Schering drug to reverse anesthesia
Government regulators dealt a major setback to Schering-Plough Corp., rejecting a highly anticipated drug designed to help patients recover from anesthesia.
2008-08-02 15:00:00
ANALYSIS-US FDA caution seen with Schering drug denial - Reuters
By Lisa Richwine WASHINGTON Reuters - The unusual rejection of an experimental drug that had unanimous support from outside experts signals further caution by the US Food and Drug Administration and increased uncertainty for investors.FDA Puts Schering-Plough Under ForbesFDA rejects Schering drug to reverse anesthesia The Associated PressCNNMoney.com - Bloomberg - MarketWatch - Wall Street Journalall 181 news articles
2008-08-02 09:19:26
Setback for a Schering-Plough Drug
Schering-Plough said regulators had rejected Bridion, its drug to reverse the effects of anesthesia that had been heralded as a breakthrough product by analysts.
2008-08-01 19:04:38
FDA rejects Schering drug to reverse anesthesia
WASHINGTON AP -- Government regulators dealt a major setback to Schering-Plough Corp., rejecting a highly anticipated drug designed to help patients recover from anesthesia....
2008-08-01 14:43:29
FDA rejects Schering drug to reverse anesthesia
Government regulators dealt a major setback to Schering-Plough Corp., rejecting a highly anticipated drug designed to help patients recover from anesthesia. The Food and Drug Administration notified the company...
2008-08-01 14:09:27

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Anesthesia May Affect Child Development

How scent brings back memories of emotional events

Acupuncture anesthesia gives child new chance

New Jersey Court Upholds Tightened Anesthesia Rules

FDA Puts Schering-Plough Under

FDA rejects Schering drug to reverse anesthesia

ANALYSIS-US FDA caution seen with Schering drug denial - Reuters

Setback for a Schering-Plough Drug

FDA rejects Schering drug to reverse anesthesia

FDA rejects Schering drug to reverse anesthesia